Needleless and Sharp-Free Anaesthesia

Needleless Electrospinning: Developments and Performances

Needleless Injection System

Even though oral route is the most preferred one, certain conditions necessitate the use of parenteral dosage form. But this route being invasive, is considered as non-patient compliant. Thus, there came a need for a more patient compliant system which led to the development of needleless injection technology. This review intends to throw light on the basic mechanisms by which this technology w...

Upward Needleless Electrospinning of Nanofibers

Polyacrylonitrile (PAN) nanofibers were prepared by a needleless electrospinning method using three rotating fiber generators, cylinder, disc and coil. The effects of the spinneret shape on the electrospinning process and resultant fiber morphology were examined. The disc spinneret needed the lowest voltage to initiate fiber formation, followed by the coil and cylinder. Compared to cylinder, th...

Opioid-free anaesthesia in three dogs

Opioid-free anaesthesia (OFA) is a relatively new and growing field in human medicine. There are multiple motivations behind this emerging practice with the recognition of several serious potential opioid-related adverse effects including opioid induced hyperalgesia, opioid tolerance and immunomodulatory effects of opioids. Opioids have long been the mainstay of veterinary anaesthesia and pain ...

Combined epidural-spinal opioid-free anaesthesia and analgesia for hysterectomy.

Postoperative nausea and vomiting (PONV) are major problems after gynaecological surgery. We studied 40 patients undergoing total abdominal hysterectomy, allocated randomly to receive opioid-free epidural-spinal anaesthesia or general anaesthesia with continuous epidural bupivacaine 15 mg h-1 or continuous bupivacaine 10 mg h-1 with epidural morphine 0.2 mg h-1, respectively, for postoperative ...